Preheat oven to 375°F (190°C) and line a baking sheet with parchment paper.
In a large bowl, thoroughly combine ground beef, garlic powder, onion powder, salt, and black pepper. Divide and shape the mixture into 12 small, uniform patties.
In a separate small bowl, combine the melted butter and minced garlic, stirring together until well blended. Set aside for brushing.
Flatten each portion of biscuit dough into a circle. Place one beef patty in the center of each circle and top with a portion of Parmesan and cheddar cheese.
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