Cook the broken lasagna sheets in a large pot of boiling salted water according to the package directions. Drain well and set aside.
Brown the ground beef, Italian sausage, and diced yellow onion in a large skillet over medium-high heat, breaking up the meat until fully cooked and no pink remains. Drain off excess grease.
Add onion powder, garlic powder, and Italian seasoning to the meat mixture. Stir in 20 pepperoni slices, 1/2 cup crumbled bacon, and the marinara sauce. Stir to combine thoroughly.
Gently fold the drained lasagna sheets into the skillet mixture, ensuring even coating and distribution throughout.
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